Yes, there is 25 years of research to back weighted vest!
A landmark study published in the Journal of Gerontology followed postmenopausal women over five years and found that long-term weighted vest exercise significantly prevented hip bone loss a primary risk factor for fracture.
A separate study in the Journal of Aging and Physical Activity found that just 12 weeks of weighted vest training in postmenopausal women reduced bone breakdown markers by 14.5% meaning the body was losing bone more slowly.
More recently, a clinical trial comparing weighted vest training directly against a control group found significant increases in both leg and total bone mineral density in the vest group, while the control group showed measurable bone decline over the same period.
The consistent finding across studies: adding a weighted load to movement is one of the most accessible and evidence-backed tools women in the menopausal transition have for slowing and in some cases reversing bone density loss.
Sources:
https://academic.oup.com/biomedgerontology/article-abstract/55/9/M489/2948038
https://journals.humankinetics.com/view/journals/japa/15/3/article-p287.xml