PureRelief uses three clinically supported light and energy therapies 660nm red light, 850nm near-infrared light, and 10Hz pulse frequency to restore cellular energy, penetrate deep inside the knee joint, and turn off the inflammatory alarm that MSM triggers when estrogen drops.
660nm Red Light Restores Cellular Energy In Depleted Joints PMC12751248 — Photobiomodulation Therapy in Medical Disciplines (2025) LED irradiation at 660nm suppresses pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 the exact same inflammatory signals that surge when estrogen declines, while restoring mitochondrial energy production so joint cells finally have the power to repair themselves.
850nm Near-Infrared Light Reaches Deep Inside The Joint PMC10687633 — Frontiers in Cell and Developmental Biology (2023) A systematic review of 10 randomized placebo-controlled trials found that photobiomodulation significantly reduces pain intensity in knee osteoarthritis specifically because near-infrared light penetrates past the surface and muscle into the connective tissue and cartilage where the actual breakdown is happening.
10Hz Pulse Frequency Turns Off The Inflammatory Alarm PMC5115773 — Photobiomodulation with Pulsed and Continuous Wave Near-Infrared Laser In a controlled study, the 10Hz pulsed group achieved a statistically significant 33% reduction in TNF-α the dominant pro-inflammatory cytokine unleashed by estrogen withdrawal while simultaneously showing a 68% increase in cytochrome c oxidase activity, directly restoring the cellular energy pathway estrogen used to maintain.